Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | FABP1 | P07148 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726825 | 0.87 | CYP19A1 (0.38) | PPARGMAPK1MAPK14 | |
| SCHEMBL11746234 | 0.85 | KDM4E (0.46) | GAAALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL11727963 | 0.83 | PPARG (0.38) | PPARGPPARA | |
| SCHEMBL11754929 | 0.82 | ABL1 (0.35) | KCNH2 | |
| SCHEMBL11752378 | 0.82 | GABRA1 (0.34) | CYP1A2SMN1; SMN2TDP1MAPK1MAPK14 | |
| SCHEMBL11724770 | 0.81 | LMNA (0.39) | SMN1; SMN2ALDH1A1TDP1HSD17B10ALOX15 | |
| SCHEMBL11750743 | 0.80 | MEN1 (0.45) | GAAPPARGPPARAALDH1A1HPGD | |
| SCHEMBL11751938 | 0.80 | PTGDR2 (0.38) | PPARGPPARAALDH1A1MAPK1MAPK14 | |
| SCHEMBL11749703 | 0.79 | MAPK1 (0.63) | CYP1A2CYP2C9CYP2C19PPARGPPARA | |
| SCHEMBL11755110 | 0.79 | KCNH2 (0.34) | CYP2C9MAPK1MAPK14KCNH2SCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053626-A | CHOLESTEROL LEVEL-LOWERING PHENOXYACETIC ACIDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-10-11 | — | — | US | disclosed |
| US-3992386-A | 4(Quinolyl)phenoxy alkanoic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-11-16 | — | — | US | disclosed |