Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 9/20 | 0.34 |
| ▸ | WNT3A | P56704 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11746241 | 0.96 | ALDH1A1 (0.35) | ALDH1A1TP53SMN1; SMN2LMNAMAPT | |
| SCHEMBL11753550 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TP53SMN1; SMN2MAPTKDM4E | |
| SCHEMBL11733551 | 0.77 | CTNNB1 (0.42) | ALDH1A1TP53SMN1; SMN2LMNAMAPT | |
| SCHEMBL11801328 | 0.72 | CTNNB1 (0.41) | ALDH1A1TP53SMN1; SMN2LMNAMAPT | |
| SCHEMBL11747287 | 0.71 | CTNNB1 (0.39) | ALDH1A1TP53SMN1; SMN2LMNAMAPT | |
| SCHEMBL11552376 | 0.71 | TTR (0.43) | ALDH1A1LMNAKDM4EHPGDNPC1 | |
| SCHEMBL7422841 | 0.71 | ALDH1A1 (0.66) | ALDH1A1TP53SMN1; SMN2LMNAMAPT | |
| SCHEMBL7483165 | 0.71 | HPGD (0.68) | ALDH1A1TP53SMN1; SMN2LMNAMAPT | |
| SCHEMBL11753611 | 0.69 | S1PR5 (0.36) | NPC1 | |
| SCHEMBL11752377 | 0.68 | CTNNB1 (0.36) | ALDH1A1TP53SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041165-A | TREATING DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1977-08-09 | — | — | US | disclosed |
| US-3937833-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-02-10 | — | — | US | disclosed |