Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.34 |
| ▸ | WNT3A | P56704 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11752369 | 0.80 | ALDH1A1 (0.36) | ALDH1A1MAPTKDM4ETP53HPGD | |
| SCHEMBL11746241 | 0.79 | ALDH1A1 (0.35) | ALDH1A1MAPTKDM4ETP53HPGD | |
| SCHEMBL619096 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTGSK3BKDM4EHIF1A | |
| SCHEMBL27570805 | 0.75 | ATM (0.59) | ALDH1A1MAPTATMPKMTSHR | |
| SCHEMBL11820732 | 0.72 | ALDH1A1 (0.46) | ALDH1A1MAPTGSK3BKDM4EHIF1A | |
| SCHEMBL11750545 | 0.72 | ALDH1A1 (0.49) | ALDH1A1MAPTGSK3BKDM4EHIF1A | |
| SCHEMBL1535157 | 0.68 | ATM (0.72) | ALDH1A1MAPTKDM4EMAPK1ATM | |
| SCHEMBL6486626 | 0.68 | CTNNB1 (0.66) | ALDH1A1MAPTKDM4EMAPK1ATM | |
| SCHEMBL10170811 | 0.68 | ALDH1A1 (0.42) | ALDH1A1MAPTGSK3BKDM4EHIF1A | |
| SCHEMBL11550016 | 0.67 | ALDH1A1 (0.54) | ALDH1A1MAPTGSK3BKDM4EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041165-A | TREATING DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1977-08-09 | — | — | US | disclosed |
| US-3937833-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-02-10 | — | — | US | disclosed |