Dl-Anabasine

Dl-Anabasine

SCHEMBL117530

c1cncc(C2CCCCN2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 10/20 1.00
CHRNA4 P43681 10/20 1.00
CHRNA7 P36544 8/20 1.00
CYP2A6 P11509 3/20 1.00
MEN1 O00255 2/20 1.00
CYP2D6 P10635 2/20 1.00
CYP2C19 P33261 2/20 1.00
KMT2A Q03164 2/20 1.00
POLB P06746 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
CYP1A2 P05177 1/20 1.00
CYP2C9 P11712 1/20 1.00
CYP11B2 P19099 1/20 0.58
AURKA O14965 1/20 0.47
ALDH1A1 P00352 2/20 0.45
CHRNB4 P30926 2/20 0.45
CHRNA3 P32297 2/20 0.45
CHRNA2 Q15822 2/20 0.45
LMNA P02545 1/20 0.45
TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Anabasine SCHEMBL15740333 1.00 CHRNB2 (1.00) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
Dl-Anabasine SCHEMBL30835558 1.00 CHRNB2 (1.00) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
Anabasine SCHEMBL29634446 1.00 CHRNB2 (1.00) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
Anabasine SCHEMBL3465120 1.00 CHRNB2 (1.00) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
SCHEMBL9673975 0.98 CHRNB2 (0.97) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
SCHEMBL9673965 0.98 CHRNB2 (0.97) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
Anabasine SCHEMBL29421176 0.98 CHRNB2 (0.97) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
Dl-Anabasine SCHEMBL1004341 0.98 CHRNB2 (0.97) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
SCHEMBL6801148 0.98 CHRNB2 (0.97) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
Dl-Anabasine SCHEMBL7194509 0.98 CHRNB2 (0.97) CHRNB2CHRNA4CHRNA7CYP2A6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12985 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122081306-A Composite microbial inoculum and preparation method and application thereof 2026-05-26 CN claimed
CN-122084339-A Purity standard substance for tobacco, tobacco products and smoke, preparation method and application thereof 2026-05-26 CN claimed
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
US-12630834-B2 Methods and compositions for regulating alkaloids in tobacco ALTRIA CLIENT SERVICES LLC (US) 2026-05-19 US claimed
US-12624365-B2 Method for modulating the alkaloid content of a tobacco plant BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) 2026-05-12 US claimed
EP-4727345-A1 TOBACCO PLANTS WITH REDUCED NICOTINIC ALKALOID LEVELS North Carolina State University (US) 2026-04-22 EP claimed
US-20260101860-A1 TOBACCO PLANTS WITH REDUCED NICOTINIC ALKALOID LEVELS UNIV NORTH CAROLINA STATE (US) 2026-04-16 US claimed
US-20250366479-A1 Non-Aqueous Organo Liquid Delivery Systems containing dispersed Organo Polycarboxylate Functionalities that improves efficiencies and properties of nitrogen sources SOILGENIC TECH LLC (US) 2025-12-04 US claimed
US-20250361222-A1 Extraction of nicotine from tobacco by closed cycle steam stripping and scrubbing SAMULIS LEOPOLD (GB) 2025-11-27 US claimed
WO-2025244856-A1 METHODS AND COMPOSITIONS RELATING TO ELQ COMPOUNDS OREGON HEALTH & SCIENCE UNIVERSITY (US) 2025-11-27 WO claimed
US-4971079-A CHEWING GUM FOR ADDICTION TO NICOTINE TALAPIN VITALY I (SU) 1990-11-20 US claimed
US-4920225-A Resolution of 1,4-dihydropyridine derivatives LABORATOIRES SYNTEX S.A. (FR) 1990-04-24 US claimed
EP-0273349-A2 Resolution of 1,4-dihydropyridine derivatives LABORATOIRES SYNTEX S.A. (FR) 1988-07-06 EP claimed
EP-0249245-A2 Antihypertensive dihydropyridine derivatives LABORATOIRES SYNTEX S.A. (FR) 1987-12-16 EP claimed
EP-0103969-B1 PRINTING INKS AND PRINTED SUBSTRATES LAWRENCE, Peter Robin Broughton (GB) 1986-10-29 EP claimed
US-4574151-A Amine salts and products containing them Lawrence, Peter Robin Broughton (GB) 1986-03-04 US claimed
US-4464434-A Microencapsulated alkaloidal material and method of producing same CELANESE CORPORATION (US) 1984-08-07 US claimed
EP-0103970-A2 Amine salts and products containing them LAWRENCE, Peter Robin Broughton (GB) 1984-03-28 EP claimed
EP-0103969-A1 Printing inks and printed substrates LAWRENCE, Peter Robin Broughton (GB) 1984-03-28 EP claimed
US-4195645-A POLYSACCHARIDES, ALKALOIDS CELANESE CORPORATION (US) 1980-04-01 US claimed