Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | GAA | P10253 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | GLA | P06280 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21794477 | 0.75 | APP (0.57) | APPMAPTGAAKDM4ENPC1 | |
| SCHEMBL6494589 | 0.74 | MAPT (0.72) | APPMAPTGAAKDM4ENPC1 | |
| SCHEMBL8393309 | 0.71 | APP (0.73) | APPMAPTGAAKDM4ENPC1 | |
| SCHEMBL11749470 | 0.71 | MAPT (0.64) | APPMAPTGAAKDM4ENPC1 | |
| SCHEMBL15496408 | 0.70 | MAPT (0.79) | APPMAPTGAAKDM4ENPC1 | |
| SCHEMBL4593965 | 0.69 | APP (0.94) | APPMAPTGAAKDM4ENPC1 | |
| SCHEMBL4604185 | 0.69 | MAPT (0.76) | APPMAPTGAAKDM4ENPC1 | |
| SCHEMBL15510887 | 0.68 | MAPT (0.77) | APPMAPTGAAKDM4ENPC1 | |
| SCHEMBL27774016 | 0.68 | APP (0.60) | APPMAPTGAAKDM4ENPC1 | |
| SCHEMBL6399498 | 0.67 | MAPT (1.00) | APPMAPTGAAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024125-A | Dis-azo pigments deriving from bis-diazotized diamino-2-phenyl-benzazolones | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |