Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11754378 | 0.94 | MAP2K4 (0.48) | MAP2K4MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL11756944 | 0.93 | MAP2K4 (0.48) | MAP2K4MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL11756806 | 0.90 | ADORA1 (0.50) | MAP2K4MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL11751350 | 0.87 | ADORA1 (0.58) | MAP2K4MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL11750053 | 0.86 | MAP2K4 (0.49) | MAP2K4MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL11751508 | 0.84 | ADORA1 (0.50) | MAPTKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL11748293 | 0.81 | ALDH1A1 (0.60) | MAP2K4MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL11755002 | 0.81 | MAP2K4 (0.46) | MAP2K4MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL11752390 | 0.79 | RXRA (0.48) | KDM4ENPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL11753382 | 0.76 | POLB (0.58) | MAPTKDM4ENPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |