Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512886 | 0.79 | GRIN2D (0.55) | NPSR1LMNATAAR1NPC1RAB9A | |
| SCHEMBL11511648 | 0.78 | GRIN2D (0.53) | LMNASMN1; SMN2TAAR1MEN1KMT2A | |
| Guanabenz SCHEMBL3054917 | 0.78 | NPSR1 (1.00) | NPSR1CYP1A2LMNACYP2D6TSHR | |
| Guanoxabenz SCHEMBL19715284 | 0.77 | SLC22A1 (0.69) | NPSR1CYP1A2LMNACYP2D6TSHR | |
| Guanoxabenz SCHEMBL122727 | 0.77 | SLC22A1 (0.69) | NPSR1CYP1A2LMNACYP2D6TSHR | |
| Guanoxabenz SCHEMBL17802522 | 0.77 | SLC22A1 (0.69) | NPSR1CYP1A2LMNACYP2D6TSHR | |
| SCHEMBL17704923 | 0.77 | SLC22A1 (0.73) | NPSR1CYP1A2LMNACYP2D6TSHR | |
| SCHEMBL8925014 | 0.76 | SLC22A1 (0.67) | NPSR1CYP1A2LMNACYP2D6TSHR | |
| SCHEMBL8925019 | 0.76 | SLC22A1 (0.67) | NPSR1CYP1A2LMNACYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL8028081 | 0.75 | SLC22A1 (0.65) | NPSR1CYP1A2LMNACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192786-A1 | STAT3 INHIBITION FOR TREATMENT AND PREVENTION OF HUMAN CORONAVIRUS INFECTION | GLG PHARMA LLC (US) | 2023-06-22 | — | — | US | disclosed |
| US-4032659-A | ADMINISTERING THIOSEMICARBAZONE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |
| US-4027039-A | ADMINISTERING AMINOGUANIDINE, GUANIDINE, OR 1-(SEC-BUTYLIDENEAMINO)GUANIDINE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |
| US-3980774-A | HYDRAZINE AND HYDRAZINE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-09-14 | — | — | US | disclosed |