Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 1/20 | 0.73 |
| ▸ | HTR1A | P08908 | 1/20 | 0.73 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.73 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.73 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.73 |
| ▸ | MAOA | P21397 | 1/20 | 0.73 |
| ▸ | DRD1 | P21728 | 1/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.73 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.73 |
| ▸ | HTR2C | P28335 | 1/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.73 |
| ▸ | DRD3 | P35462 | 1/20 | 0.73 |
| ▸ | HTR2B | P41595 | 1/20 | 0.73 |
| ▸ | MTOR | P42345 | 1/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanabenz SCHEMBL219392 | 0.85 | TAAR1 (1.00) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| Guanabenz SCHEMBL15390 | 0.85 | TAAR1 (1.00) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| Guanabenz SCHEMBL3054917 | 0.83 | NPSR1 (1.00) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| SCHEMBL22761365 | 0.81 | SLC22A1 (0.67) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| Guanoxabenz SCHEMBL122727 | 0.79 | SLC22A1 (0.69) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| Guanoxabenz SCHEMBL17802522 | 0.79 | SLC22A1 (0.69) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| Guanoxabenz SCHEMBL19715284 | 0.79 | SLC22A1 (0.69) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| SCHEMBL8925019 | 0.77 | SLC22A1 (0.67) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| SCHEMBL8925014 | 0.77 | SLC22A1 (0.67) | SLC22A1HTR1AADRA2ACHRM1ADRA2B | |
| SCHEMBL11754270 | 0.77 | NPSR1 (0.63) | SLC22A1HTR1AADRA2ACHRM1ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160113893-A1 | NEW THERAPEUTIC USES OF ENZYME INHIBITORS | UPSHER-SMITH LABORATORIES, INC. | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160113893-A1 | NEW THERAPEUTIC USES OF ENZYME INHIBITORS | VAPB, VAPA, AOX1 | SLC22A1 2475/4885HTR1A 3761/4885ADRA2A 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.