Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757725 | 0.84 | KMT2A (0.49) | GAASMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL18622660 | 0.78 | FERMT2 (0.50) | GAANOX1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11759204 | 0.78 | GAA (0.33) | GAASMN1; SMN2MAPTALDH1A1POLB | |
| SCHEMBL23182885 | 0.76 | SMN1; SMN2 (0.47) | GAANOX1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11246752 | 0.76 | SMN1; SMN2 (0.59) | GAANOX1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7655772 | 0.76 | SMN1; SMN2 (0.48) | GAANOX1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7655919 | 0.76 | FERMT2 (0.52) | GAANOX1SMN1; SMN2MAPTHTT | |
| SCHEMBL6929125 | 0.75 | GAA (0.70) | GAANOX1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL14000123 | 0.75 | GAA (0.49) | GAANOX1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11855565 | 0.72 | NOX1 (0.65) | GAANOX1SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031186-A | ANTISECRETORY AGENTS | ROHM AND HAAS COMPANY (US) | 1977-06-21 | — | — | US | claimed |
| US-4031186-A | ANTISECRETORY AGENTS | ROHM AND HAAS COMPANY (US) | 1977-06-21 | — | — | US | disclosed |