Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 10/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14000063 | 0.78 | FFAR1 (0.42) | GAAL3MBTL1 | |
| SCHEMBL14000133 | 0.77 | GUCY1A1 (0.51) | GAAALDH1A1MAPTKDM4EMAPK1 | |
| Oxalic Acid SCHEMBL5009452 | 0.76 | MEN1 (0.45) | GAAL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL7655919 | 0.75 | FERMT2 (0.52) | GAAMAPTSMN1; SMN2NOX1 | |
| SCHEMBL18622660 | 0.75 | FERMT2 (0.50) | GAAALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL11754633 | 0.75 | GAA (0.56) | GAAL3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL13999721 | 0.74 | ALDH1A1 (0.49) | ALDH1A1MAPTTDP1HPGDKDM4E | |
| SCHEMBL11864091 | 0.74 | MAPK1 (0.44) | GAAEGFRL3MBTL1ALDH1A1MAPT | |
| SCHEMBL8725948 | 0.73 | SMN1; SMN2 (0.64) | GAAALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL23182885 | 0.73 | SMN1; SMN2 (0.47) | GAAEGFRL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009005-A1 | AZOLECARBOXAMIDE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |