Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 11/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 3/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 6/20 | 0.44 |
| ▸ | RXRB | P28702 | 6/20 | 0.44 |
| ▸ | RXRG | P48443 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | C5 | P01031 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11753014 | 1.00 | KMT2A (0.51) | KMT2AMEN1NR4A2NR4A1NR4A3 | |
| SCHEMBL11751140 | 0.93 | KMT2A (0.40) | KMT2AMEN1NR4A2NR4A1NR4A3 | |
| SCHEMBL2744315 | 0.89 | NR4A2 (0.60) | KMT2ANR4A2NR4A1NR4A3RXRA | |
| SCHEMBL11755317 | 0.85 | RXRA (0.44) | KMT2AMEN1NR4A2MAPTRXRA | |
| SCHEMBL11753981 | 0.85 | RXRA (0.44) | KMT2AMEN1NR4A2MAPTRXRA | |
| SCHEMBL11747816 | 0.83 | NR4A2 (0.50) | KMT2ANR4A2NR4A1NR4A3MAPT | |
| SCHEMBL11752428 | 0.83 | RXRA (0.55) | KMT2ANR4A2NR4A1NR4A3MAPT | |
| SCHEMBL11752646 | 0.83 | CYP2C19 (0.51) | KMT2ANR4A2NR4A1NR4A3RXRA | |
| SCHEMBL11752538 | 0.83 | RXRA (0.55) | KMT2AMEN1NR4A2NR4A1NR4A3 | |
| SCHEMBL11748650 | 0.83 | NR4A2 (0.59) | KMT2AMEN1NR4A2NR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |