Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.44 |
| ▸ | RXRB | P28702 | 3/20 | 0.44 |
| ▸ | RXRG | P48443 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11753981 | 1.00 | RXRA (0.44) | RXRARXRBRXRGCNR1MEN1 | |
| SCHEMBL11262728 | 0.92 | RXRA (0.46) | RXRARXRBRXRGCNR1MEN1 | |
| SCHEMBL11751140 | 0.92 | KMT2A (0.40) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL11752832 | 0.85 | RXRA (0.55) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL11752538 | 0.85 | RXRA (0.55) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL11754855 | 0.85 | KMT2A (0.51) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL11753014 | 0.85 | KMT2A (0.51) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL11751493 | 0.84 | NPC1 (0.49) | RXRARXRBRXRGCNR1TP53 | |
| SCHEMBL11753438 | 0.84 | NR4A2 (0.41) | RXRARXRBRXRGCNR1MEN1 | |
| SCHEMBL11756164 | 0.84 | NR4A2 (0.41) | RXRARXRBRXRGCNR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |