Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11755900 | 0.95 | L3MBTL1 (0.48) | L3MBTL1HDAC1HDAC6MAPK14RAB9A | |
| SCHEMBL11757371 | 0.94 | HDAC1 (0.48) | L3MBTL1HDAC1HDAC6RAB9ANPC1 | |
| SCHEMBL11752862 | 0.85 | KDM4E (0.50) | MAPK14RAB9ANPC1ADORA1ALDH1A1 | |
| SCHEMBL11751581 | 0.84 | MAPK14 (0.49) | MAPK14ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL11752527 | 0.84 | KMT2A (0.49) | L3MBTL1MAPK14RAB9ANPC1ALDH1A1 | |
| SCHEMBL11752080 | 0.81 | ALDH1A1 (0.45) | L3MBTL1MAPK14RAB9ANPC1ALDH1A1 | |
| SCHEMBL11753979 | 0.81 | MAPK14 (0.47) | MAPK14ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL11749158 | 0.81 | MAPK14 (0.47) | MAPK14ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL11751584 | 0.81 | KDM4E (0.47) | RAB9ANPC1ALDH1A1HPGDKDM4E | |
| SCHEMBL11752064 | 0.80 | ADORA2A (0.55) | MAPK14ALDH1A1HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |