Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.56 |
| ▸ | RXRB | P28702 | 8/20 | 0.56 |
| ▸ | RXRG | P48443 | 8/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11745189 | 0.94 | RXRA (0.56) | RXRARXRBRXRGNR4A2NPC1 | |
| SCHEMBL11754925 | 0.94 | RXRA (0.49) | RXRARXRBRXRGNR4A2NPC1 | |
| SCHEMBL11751845 | 0.85 | RXRA (0.44) | RXRARXRBRXRGNR4A2NPC1 | |
| SCHEMBL11749454 | 0.85 | RXRA (0.44) | RXRARXRBRXRGNR4A2NPC1 | |
| SCHEMBL11752538 | 0.84 | RXRA (0.55) | RXRARXRBRXRGNR4A2TSHR | |
| SCHEMBL11752605 | 0.84 | RXRA (0.59) | RXRARXRBRXRGNR4A2NPC1 | |
| SCHEMBL11752832 | 0.84 | RXRA (0.55) | RXRARXRBRXRGNR4A2TSHR | |
| SCHEMBL2744315 | 0.83 | NR4A2 (0.60) | RXRARXRBRXRGNR4A2NPC1 | |
| SCHEMBL11752044 | 0.81 | NPC1 (0.49) | RXRARXRBRXRGNR4A2NPC1 | |
| SCHEMBL11754193 | 0.81 | RXRA (0.45) | RXRARXRBRXRGNR4A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |