Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.85 |
| ▸ | AR | P10275 | 6/20 | 0.85 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.85 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.85 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.83 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.83 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.83 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.65 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 2/20 | 0.65 |
| ▸ | MLNR | O43193 | 1/20 | 0.65 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93664 | 0.92 | NR3C1 (0.85) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL11875376 | 0.92 | NR3C1 (0.85) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL11125210 | 0.92 | NR3C1 (0.85) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL11600203 | 0.92 | NR3C1 (0.85) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL11748063 | 0.92 | NR3C1 (0.85) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL11600201 | 0.92 | NR3C1 (0.85) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL3164036 | 0.92 | NR3C1 (0.85) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL11125211 | 0.92 | NR3C1 (0.85) | PGRARADORA3CHRM1ADRA1A | |
| Halobetasol Propionate SCHEMBL17190306 | 0.92 | PGR (1.00) | PGRARADORA3CHRM1ADRA1A | |
| Halobetasol Propionate SCHEMBL1650038 | 0.92 | PGR (1.00) | PGRARADORA3CHRM1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021459-A | Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy 20-keto-pregnenes | SCHERING CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |