Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5057119 | 0.89 | KDM4E (0.69) | KDM4EXDHTSHRCYP3A4EPHX1 | |
| SCHEMBL1107710 | 0.85 | KDM4E (0.63) | KDM4EXDHTSHRCYP3A4EPHX1 | |
| SCHEMBL5023065 | 0.83 | MRGPRX1 (0.47) | KDM4ETSHRCYP3A4HCRTR1ALDH1A1 | |
| SCHEMBL10497899 | 0.81 | CYP3A4 (0.68) | KDM4EXDHTSHRCYP3A4EPHX1 | |
| SCHEMBL11759794 | 0.80 | ALDH1A1 (0.61) | KDM4EXDHTSHRCYP3A4EPHX1 | |
| SCHEMBL28045267 | 0.80 | KDM4E (0.57) | KDM4EXDHTSHRCYP3A4EPHX1 | |
| SCHEMBL4729840 | 0.80 | KDM4E (0.57) | KDM4EXDHTSHRCYP3A4EPHX1 | |
| SCHEMBL11757434 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1NPC1MAPTNPSR1 | |
| SCHEMBL5057136 | 0.79 | KDM4E (0.53) | KDM4ENPC1 | |
| SCHEMBL5052478 | 0.79 | KDM4E (0.56) | KDM4ETSHRCYP3A4ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054719-A | ACRYLIC ESTER, TERTIARY AMINE | AMERICAN CYANAMID COMPANY (US) | 1977-10-18 | — | — | US | disclosed |