Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PDE6D | O43924 | 1/20 | 0.52 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.52 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL715533 | 0.84 | ALDH1A1 (0.68) | KDM4EALDH1A1HPGDMAPTHTT | |
| SCHEMBL5009162 | 0.83 | KDM4E (0.77) | KDM4EALDH1A1HPGDMAPTHTT | |
| SCHEMBL15987699 | 0.81 | MEN1 (0.58) | KDM4EALDH1A1HPGDMAPTHTT | |
| SCHEMBL230641 | 0.79 | ALDH1A1 (0.70) | KDM4EALDH1A1HPGDMAPTHTT | |
| SCHEMBL19275978 | 0.77 | KDM4E (0.77) | KDM4EALDH1A1HPGDMAPTHTT | |
| SCHEMBL12116699 | 0.75 | CYP11B2 (0.70) | KDM4EALDH1A1HPGDMAPTHTT | |
| SCHEMBL27987926 | 0.75 | ESR2 (0.58) | KDM4EALDH1A1HPGDMAPTHTT | |
| SCHEMBL231419 | 0.75 | KDM4E (0.64) | KDM4EALDH1A1HPGDMAPTHTT | |
| SCHEMBL11313561 | 0.75 | KDM4E (0.73) | KDM4EALDH1A1HPGDMAPTHTT | |
| SCHEMBL18969121 | 0.75 | KDM4E (0.73) | KDM4EALDH1A1HPGDMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065427-A | Polychromophoric heterocyclic ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4000148-A | POLYMERS | EASTMAN KODAK COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-3981822-A | HETEROCYCLIC COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1976-09-21 | — | — | US | disclosed |