Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10665310 | 0.82 | CYP1A2 (0.60) | MASP2F2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL28281433 | 0.82 | MASP2 (0.56) | MASP2F2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL19175209 | 0.80 | MASP2 (0.51) | MASP2F2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL3451299 | 0.80 | MASP2 (0.51) | MASP2F2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL3453162 | 0.80 | MASP2 (0.51) | MASP2F2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL10980033 | 0.80 | MAPT (0.61) | MASP2F2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28663076 | 0.80 | CYP1A2 (0.41) | MASP2F2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL10897086 | 0.79 | MASP2 (0.50) | MASP2F2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL10352817 | 0.79 | MASP2 (0.50) | MASP2F2MAPTALDH1A1CYP3A4 | |
| SCHEMBL10352026 | 0.79 | LMNA (0.53) | MASP2F2MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031232-A | 1-Alkyl-2-(phenoxymethyl)-5-nitro-imidazoles and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-06-21 | — | — | US | disclosed |