Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11754921 | 0.86 | ALDH1A1 (0.45) | KMT2ASMN1; SMN2ALDH1A1MAPK1TP53 | |
| SCHEMBL11752156 | 0.77 | F2 (0.40) | F2NR4A2ADORA2AADORA1KMT2A | |
| SCHEMBL11751236 | 0.67 | KDM4E (0.40) | ADORA1KMT2ASMN1; SMN2NPC1MAPT | |
| SCHEMBL11752345 | 0.66 | MAP3K14 (0.40) | KMT2ASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL8682362 | 0.65 | KMT2A (0.43) | F2KMT2ASMN1; SMN2POLBMAPT | |
| SCHEMBL11752453 | 0.65 | ALDH1A1 (0.46) | KMT2ASMN1; SMN2MAPTALDH1A1MAPK1 | |
| SCHEMBL11779970 | 0.63 | IRAK4 (0.41) | KMT2AHSD17B10 | |
| SCHEMBL8538654 | 0.63 | PRMT5 (0.37) | MAOBPRMT5KMT2AALDH1A1CCR4 | |
| SCHEMBL21497068 | 0.62 | MEN1 (0.51) | KMT2ANPC1MAPTPKMRAB9A | |
| SCHEMBL11752876 | 0.62 | TSHR (0.47) | F2KMT2ASMN1; SMN2POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051252-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |