Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.38 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560772 | 0.68 | CYP11B2 (0.42) | DYRK1AMMP13PIN1KMT2A | |
| SCHEMBL17112168 | 0.67 | GAA (0.46) | CDK8CLK4DYRK1AKMT2ACYP2D6 | |
| SCHEMBL11754180 | 0.67 | ELANE (0.47) | KCNH2GUCY1A1GUCY1B1HSD17B10 | |
| SCHEMBL11752052 | 0.67 | ADORA2A (0.46) | KMT2AHSD17B10 | |
| SCHEMBL11752029 | 0.66 | MAPT (0.51) | KMT2A | |
| SCHEMBL922232 | 0.66 | MAP2K4 (0.41) | IRAK4CCNCCDK8KCNH2GUCY1A1 | |
| SCHEMBL6072062 | 0.66 | ALDH1A1 (0.46) | DYRK1AKMT2AHSD17B10 | |
| SCHEMBL6072059 | 0.66 | ALDH1A1 (0.46) | DYRK1AKMT2AHSD17B10 | |
| SCHEMBL5566519 | 0.64 | CYP11B2 (0.43) | DYRK1AMMP13PIN1 | |
| SCHEMBL22536418 | 0.64 | PDK1 (0.43) | CLK1DYRK1AGAKRIPK2COQ8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051252-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |