Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11762772 | 0.89 | POLB (0.52) | POLBHTTCYP1A2MEN1KMT2A | |
| SCHEMBL11759881 | 0.87 | CYP1A2 (0.48) | POLBHTTCYP1A2MEN1KMT2A | |
| SCHEMBL11761064 | 0.81 | CYP1A2 (0.56) | CYP1A2MEN1KMT2AHPGDMAPT | |
| SCHEMBL11758289 | 0.75 | MEN1 (0.49) | POLBHTTCYP1A2MEN1KMT2A | |
| SCHEMBL11758305 | 0.71 | NR1H4 (0.54) | POLBMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11764247 | 0.69 | PLG (0.56) | POLBHPGDMAPTSMN1; SMN2NPC1 | |
| SCHEMBL11067456 | 0.68 | ACHE (0.46) | POLBHTTCYP1A2MEN1KMT2A | |
| SCHEMBL29492899 | 0.67 | ESR1 (0.70) | TDP1 | |
| SCHEMBL2614950 | 0.67 | ESR1 (0.70) | TDP1 | |
| SCHEMBL13898693 | 0.67 | HSP90AA1 (0.50) | POLBHTTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008274-A | ANTIFOULING | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1977-02-15 | — | — | US | disclosed |