SCHEMBL2614950

SCHEMBL2614950

CCC(C)(C)c1ccc(O)c(C)c1

nearest known ligand 0.70

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 17/20 0.70
ESR2 Q92731 9/20 0.70
AR P10275 4/20 0.70
VDR P11473 1/20 0.48
TP53 P04637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29492899 1.00 ESR1 (0.70) ESR1ESR2ARVDRTP53
SCHEMBL4401972 0.86 ESR1 (0.52) ESR1ESR2ARTDP1
SCHEMBL56223 0.85 ALDH1A1 (0.61) ESR1ESR2ARTDP1
SCHEMBL29499858 0.83 ESR1 (0.70) ESR1ESR2ARVDRTP53
SCHEMBL11319965 0.83 ESR1 (0.70) ESR1ESR2ARVDRTP53
SCHEMBL30596871 0.83 ESR1 (0.70) ESR1ESR2ARVDRTP53
SCHEMBL312794 0.83 ESR1 (0.70) ESR1ESR2ARVDRTP53
SCHEMBL30058620 0.83 ESR1 (1.00) ESR1ESR2ARVDR
SCHEMBL837374 0.83 ESR1 (1.00) ESR1ESR2ARVDR
SCHEMBL80891 0.82 MAPK1 (0.48) ESR1ESR2ARTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070056901-A1 Solvent-resistant membranes from solvent-inert polyimides and polyketones GENERAL ELECTRIC COMPANY 2007-03-15 US claimed
US-20250388541-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-12-25 US disclosed
EP-4511117-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN Vertex Pharmaceuticals Incorporated (US) 2025-02-26 EP disclosed
EP-4511114-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN Vertex Pharmaceuticals Incorporated (US) 2025-02-26 EP disclosed
US-20240219830-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-07-04 US disclosed
US-20240210824-A1 CARBOXYLATE, CARBOXYLIC ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-06-27 US disclosed
EP-3377473-B1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX PHARMACEUTICALS INC (US) 2024-06-19 EP disclosed
US-11874601-B2 Resist composition, method of forming resist pattern, compound, and acid diffusion-controlling agent TOKYO OHKA KOGYO CO., LTD. (JP) 2024-01-16 US disclosed
US-11840503-B2 Salt, acid generator, resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-12-12 US disclosed
US-11835857-B2 Resist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2023-12-05 US disclosed
US-20070060688-A1 Solvent-resistant membranes from solvent-inert polyimides and polyketones GENERAL ELECTRIC COMPANY 2007-03-15 US disclosed
US-20070056901-A1 Solvent-resistant membranes from solvent-inert polyimides and polyketones GENERAL ELECTRIC COMPANY 2007-03-15 US disclosed
US-20070042997-A1 Medicament for treatment of dermal pigmentation INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2007-02-22 US disclosed
US-20070042997-A1 Medicament for treatment of dermal pigmentation INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2007-02-22 US disclosed
EP-0733695-A1 Mannich base derivatives, and the production and uses thereof ETHYL CORPORATION (US) 1996-09-25 EP disclosed
US-5558683-A FUEL ADDITIVE ETHYL CORPORATION (US) 1996-09-24 US disclosed
US-5387266-A Detergent-dispersant additives for fuels and lubricants ETHYL CORPORATION (US) 1995-02-07 US disclosed
US-4219570-A Insect repellents and a method of repelling insects AJINOMOTO COMPANY, INCORPORATED (JP) 1980-08-26 US disclosed
US-4013640-A SOLVENT EXTRACTION, DISTILLATION UNION CARBIDE CORPORATION (US) 1977-03-22 US disclosed
US-3998804-A PROCESS FOR COUPLING OF WATER-INSOLUBLE 2,4-DISUBSTITUTED PHENOLS WITH DIAZOTIZED O-NITROANILINES CIBA-GEIGY CORPORATION (US) 1976-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240210824-A1 CARBOXYLATE, CARBOXYLIC ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SCO2, CBR1, OXGR1 ESR1 801/4885ESR2 1960/4885AR 2165/4885
US-20250388541-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN SCN1B, CLIC1, HCN1 ESR1 4705/4885ESR2 2963/4885AR 2675/4885
US-11874601-B2 Resist composition, method of forming resist pattern, compound, and acid diffusion-controlling agent MRPS23, MRPS22, SLC11A2 ESR1 1351/4885ESR2 806/4885AR 716/4885
US-20240219830-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN H1-0, HCN3, RER1 ESR1 1780/4885ESR2 3148/4885AR 2250/4885
US-20070042997-A1 Medicament for treatment of dermal pigmentation TYR, XDH, XPA ESR1 3695/4885ESR2 2631/4885AR 254/4885
US-11840503-B2 Salt, acid generator, resist composition and method for producing resist pattern RER1, H1-0, CA7 ESR1 1209/4885ESR2 2661/4885AR 1355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.