SCHEMBL1275936

SCHEMBL1275936

Cc1cc(O)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.71
RAB9A P51151 8/20 0.71
LMNA P02545 1/20 0.68
POLB P06746 3/20 0.62
ALDH1A1 P00352 6/20 0.49
SMN1; SMN2 Q16637 5/20 0.49
KDM4E B2RXH2 6/20 0.48
SELL P14151 1/20 0.43
SELP P16109 1/20 0.43
SELE P16581 1/20 0.43
MAPT P10636 6/20 0.41
HPGD P15428 5/20 0.41
TDP1 Q9NUW8 2/20 0.41
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
IGF2BP2 Q9Y6M1 1/20 0.38
THRB P10828 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL110113 0.86 NPC1 (0.71) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL7703339 0.86 NPC1 (0.71) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL29489567 0.86 NPC1 (0.71) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL105385 0.83 NPC1 (0.68) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL9408736 0.83 NPC1 (0.68) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL10598824 0.83 NPC1 (1.00) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL18375849 0.83 NPC1 (0.68) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL258759 0.82 NPC1 (0.66) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL31267541 0.82 NPC1 (0.66) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL20365734 0.82 NPC1 (0.66) NPC1RAB9ALMNAPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11078419-B2 Substituted benzotriazole phenolate salts and antioxidant compositions formed therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-08-03 US disclosed
US-11053373-B2 Polymeric matrices with ionic additives 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-07-06 US disclosed
US-10724171-B2 Electret webs with charge-enhancing additives 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-07-28 US disclosed
US-20200172809-A1 SUBSTITUTED BENZOTRIAZOLE PHENOLATE SALTS AND ANTIOXIDANT COMPOSITIONS FORMED THEREFROM 3M INNOVATIVE PROPERTIES CO (US) 2020-06-04 US disclosed
US-10669481-B2 Substituted benzotriazole phenolate salts and antioxidant compositions formed therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-06-02 US disclosed
US-20190003112-A1 ELECTRET WEBS WITH CHARGE-ENHANCING ADDITIVES 3M INNOVATIVE PROPERTIES COMPANY 2019-01-03 US disclosed
US-20180195000-A1 SUBSTITUTED BENZOTRIAZOLE PHENOLATE SALTS AND ANTIOXIDANT COMPOSITIONS FORMED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2018-07-12 US disclosed
US-7892443-B2 Method of manufacturing member with concave portions, member with concave portions, lens substrate, transmission type screen and rear projection SEIKO EPSON CORPORATION (JP) 2011-02-22 US disclosed
US-7349159-B2 Mold for manufacturing a microlens substrate, a method of manufacturing microlens substrate, a microlens substrate, a transmission screen, and a rear projection SEIKO EPSON CORPORATION (JP) 2008-03-25 US disclosed
US-7265909-B2 Lens substrate, a transmission screen and a rear projection device SEIKO EPSON CORPORATION (JP) 2007-09-04 US disclosed
US-20070166849-A1 Method of manufacturing member with concave portions, member with concave portions, lens substrate, transmission type screen and rear projection SEIKO EPSON CORPORATION 2007-07-19 US disclosed
US-20060087741-A1 Mold for manufacturing a microlens substrate, a method of manufacturing microlens substrate, a microlens substrate, a transmission screen, and a rear projection SEIKO EPSON CORPORATION 2006-04-27 US disclosed
US-20060087025-A1 Method of manufacturing a substrate with concave portions, a substrate with concave portions, a microlens substrate, a transmission screen, and a rear projection SEIKO EPSON CORPORATION 2006-04-27 US disclosed
US-20060087742-A1 Method of manufacturing a microlens substrate, a substrate with concave portions, a microlens substrate, a transmission screen, and a rear projection SEIKO EPSON CORPORATION 2006-04-27 US disclosed
US-20060082902-A1 Lens substrate, a method of manufacturing a lens substrate, a transmission screen and a rear projection SEIKO EPSON CORPORATION 2006-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172809-A1 SUBSTITUTED BENZOTRIAZOLE PHENOLATE SALTS AND ANTIOXIDANT COMPOSITIONS FORMED THEREFROM COMT, OGFOD1, TYR NPC1 4227/4885RAB9A 4875/4885LMNA 3383/4885
US-10669481-B2 Substituted benzotriazole phenolate salts and antioxidant compositions formed therefrom COMT, OGFOD1, TYR NPC1 4227/4885RAB9A 4875/4885LMNA 3383/4885
US-11078419-B2 Substituted benzotriazole phenolate salts and antioxidant compositions formed therefrom COMT, OGFOD1, TYR NPC1 4227/4885RAB9A 4875/4885LMNA 3383/4885
US-20180195000-A1 SUBSTITUTED BENZOTRIAZOLE PHENOLATE SALTS AND ANTIOXIDANT COMPOSITIONS FORMED THEREFROM COMT, OGFOD1, TYR NPC1 4227/4885RAB9A 4875/4885LMNA 3383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.