Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 7/20 | 0.87 |
| ▸ | APEX1 | P27695 | 2/20 | 0.59 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.48 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | CD40 | P25942 | 3/20 | 0.46 |
| ▸ | CD40LG | P29965 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11763856 | 0.93 | ENPP2 (0.96) | ENPP2APEX1SUMO2SUMO1SENP7 | |
| SCHEMBL11758959 | 0.89 | ENPP2 (0.91) | ENPP2APEX1SUMO2SUMO1SENP7 | |
| SCHEMBL11758945 | 0.89 | ENPP2 (0.91) | ENPP2APEX1SUMO2SUMO1SENP7 | |
| SCHEMBL3410648 | 0.87 | APEX1 (0.77) | ENPP2APEX1SUMO2SUMO1SENP7 | |
| SCHEMBL11758267 | 0.87 | APEX1 (0.77) | ENPP2APEX1SUMO2SUMO1SENP7 | |
| SCHEMBL29637807 | 0.86 | ENPP2 (0.85) | ENPP2APEX1SUMO2SUMO1SENP7 | |
| SCHEMBL30716918 | 0.86 | ENPP2 (0.85) | ENPP2APEX1SUMO2SUMO1SENP7 | |
| SCHEMBL10891071 | 0.86 | ENPP2 (0.85) | ENPP2APEX1SUMO2SUMO1SENP7 | |
| SCHEMBL11594349 | 0.86 | ENPP2 (0.85) | ENPP2APEX1SUMO2SUMO1SENP7 | |
| SCHEMBL10891093 | 0.86 | ENPP2 (0.85) | ENPP2APEX1SUMO2SUMO1SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008320-A | Amidophenyl-azo-naphthalenesulfonic complement inhibitors and method of use thereof | AMERICAN CYANAMID COMPANY (US) | 1977-02-15 | — | — | US | claimed |
| US-4008320-A | Amidophenyl-azo-naphthalenesulfonic complement inhibitors and method of use thereof | AMERICAN CYANAMID COMPANY (US) | 1977-02-15 | — | — | US | disclosed |