Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | GFER | P55789 | 1/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CFTR | P13569 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529190 | 0.93 | KDM4E (0.66) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL421466 | 0.88 | IKBKB (0.65) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL11626581 | 0.86 | KDM4E (0.78) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL29498389 | 0.85 | KMT2A (1.00) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL352643 | 0.85 | KMT2A (1.00) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL1954450 | 0.85 | KMT2A (1.00) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL11685663 | 0.83 | KDM4E (0.63) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL1015993 | 0.83 | KDM4E (0.55) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL29481401 | 0.83 | KDM4E (0.55) | KDM4EKMT2AGFERRXFP1ALDH1A1 | |
| SCHEMBL4264458 | 0.83 | ABL1 (0.61) | KDM4EKMT2AGFERRXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053464-A | DISAZO PIGMENTS CONTAINING ETHER SUBSTITUTED ALKOXY CARBONYL GROUPS | CIBA-GEIGY CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |