SCHEMBL352643

SCHEMBL352643

Nc1ccc(-c2ccc(N)c(C(=O)O)c2)cc1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 1.00
KDM4E B2RXH2 2/20 1.00
GFER P55789 1/20 1.00
RXFP1 Q9HBX9 1/20 1.00
MCL1 Q07820 6/20 0.65
TDP1 Q9NUW8 3/20 0.65
MEN1 O00255 2/20 0.65
USP2 O75604 1/20 0.65
POLB P06746 1/20 0.65
MAPT P10636 1/20 0.65
THRB P10828 1/20 0.65
PKM P14618 1/20 0.65
APEX1 P27695 1/20 0.65
RECQL P46063 1/20 0.65
BLM P54132 1/20 0.65
GLA P06280 1/20 0.63
KEAP1 Q14145 1/20 0.63
IKBKB O14920 1/20 0.62
ALDH1A1 P00352 2/20 0.61
CDC25B P30305 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29498389 1.00 KMT2A (1.00) KMT2AKDM4EGFERRXFP1MCL1
SCHEMBL1954450 1.00 KMT2A (1.00) KMT2AKDM4EGFERRXFP1MCL1
Hydrochloric Acid SCHEMBL8024368 0.98 KMT2A (0.95) KMT2AKDM4EGFERRXFP1MCL1
Ammonia Solution, Strong SCHEMBL5271744 0.98 KMT2A (0.95) KMT2AKDM4EGFERRXFP1MCL1
SCHEMBL3865083 0.98 KMT2A (0.95) KMT2AKDM4EGFERRXFP1MCL1
Methane SCHEMBL29001097 0.98 KMT2A (0.95) KMT2AKDM4EGFERRXFP1MCL1
Water SCHEMBL28033099 0.98 KMT2A (0.95) KMT2AKDM4EGFERRXFP1MCL1
SCHEMBL30030661 0.92 KDM4E (0.84) KMT2AKDM4EGFERRXFP1MCL1
SCHEMBL1708790 0.92 KDM4E (0.84) KMT2AKDM4EGFERRXFP1MCL1
SCHEMBL10713802 0.92 KMT2A (0.84) KMT2AKDM4EGFERRXFP1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117718078-B Hydrophilic covalent organic framework catalyst for stably anchoring transition metal ions and preparation method and application thereof CHINA UNIVERSITY OF PETROLEUM (EAST CHINA) (CN) 2026-05-26 CN claimed
US-20260042084-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2026-02-12 US claimed
EP-4680369-A1 SYSTEMS FOR CARBON DIOXIDE CAPTURE USING FUNCTIONALIZED SORBENTS AND WATER MANAGEMENT GE Vernova Technology GmbH (CH) 2026-01-21 EP claimed
WO-2025238576-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION Nuovo Pignone Tecnologie – S.r.l. (IT) 2025-11-20 WO claimed
US-20250354659-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION NUOVO PIGNONE TECNOLOGIE – S R L (IT) 2025-11-20 US claimed
EP-4572884-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP General Electric Technology GmbH (CH) 2025-06-25 EP claimed
EP-4556112-A2 SORBENT COMPOSITIONS, SYSTEMS, AND METHODS General Electric Technology GmbH (CH) 2025-05-21 EP claimed
CN-119869460-A Sorbent compositions, systems, and methods 通用电气技术有限公司 2025-04-25 CN claimed
US-12263464-B2 Method for in-situ synthesis of metal organic frameworks (MOFs), covalent organic frameworks (COFs) and zeolite imidazolate frameworks (ZIFs), and applications thereof DESICCANT ROTORS INTERNATIONAL PRIVATE LIMITED (IN) 2025-04-01 US claimed
CN-118908184-B Preparation method and application of boron-nitrogen co-doped porous carbon material 泰苓科技(湖州)有限公司 2025-02-25 CN claimed
EP-0606013-A1 Polymer scale preventive agent Shin-Etsu Chemical Co., Ltd. (JP) 1994-07-13 EP claimed
US-5281690-A Multilayer element with polymer layers BREWER SCIENCE, INC. (US) 1994-01-25 US claimed
US-5270431-A Preparation of oligomeric or polymeric radiation-reactive intermediates for solvent-structured layers BASF AKTIENGESELLSCHAFT (DE) 1993-12-14 US claimed
US-5189154-A Ink jet printing dyes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-02-23 US claimed
EP-0303069-B1 PROCESS FOR THE PREPARATION OF OLIGOMERIC OR POLYMERIC RADIATION-REACTIVE PREADDUCTS FOR SOLVENT-STRUCTURED COATINGS BASF Aktiengesellschaft (DE) 1992-06-24 EP claimed
WO-1990012051-A1 BASE-SOLUBLE POLYIMIDE RELEASE LAYERS FOR USE IN MICROLITHOGRAPHIC PROCESSING BREWER SCIENCE, INC. (US) 1990-10-18 WO claimed
US-4520075-A ADHESION, WATERPROOF COATING NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1985-05-28 US claimed
US-4499252-A Process for producing polyimide precursor NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1985-02-12 US claimed
EP-0027506-B1 PRECURSORS OF POLYIMIDES, POLYISOINDOLOQUINAZOLINE DIONES, POLYOXAZINE DIONES AND POLYQUINAZOLINE DIONES, THEIR PREPARATION AND USE SIEMENS AKTIENGESELLSCHAFT (DE) 1983-05-11 EP claimed
EP-0027506-A1 Precursors of polyimides, polyisoindoloquinazoline diones, polyoxazine diones and polyquinazoline diones, their preparation and use SIEMENS AKTIENGESELLSCHAFT (DE) 1981-04-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042084-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP SRMS, TYRO3, SELE KMT2A 2367/4885KDM4E 421/4885GFER 355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.