Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | IKBKB | O14920 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015993 | 1.00 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL29543806 | 0.98 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL7529190 | 0.90 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL21857075 | 0.87 | ALDH1A1 (0.58) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL165608 | 0.86 | ALDH1A1 (0.62) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL21798946 | 0.86 | ALDH1A1 (0.51) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL21798893 | 0.86 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL421466 | 0.85 | IKBKB (0.65) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL4264458 | 0.84 | ABL1 (0.61) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL11758709 | 0.83 | KDM4E (0.72) | KDM4EALDH1A1HSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239931-A | As P2X3Aminoquinazoline derivatives of inhibitors | 奇斯药制品公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-114269432-B | As P2X3Aminoquinazoline derivatives of inhibitors | 奇斯药制品公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-113891745-B | As P2X3Aminoquinazoline derivatives of inhibitors | 奇斯药制品公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-116601149-A | Aminoquinazoline derivatives as P2X3 inhibitors | 奇斯药制品公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-114269432-A | As P2X3Aminoquinazoline derivatives as inhibitors | 奇斯药制品公司 | 2022-04-01 | — | — | CN | disclosed |