Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 5/20 | 0.41 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.41 |
| ▸ | RHEB | Q15382 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757703 | 0.90 | SLC6A4 (0.44) | MEN1KMT2ASLC6A4KDM4EMAPT | |
| SCHEMBL11759797 | 0.90 | MEN1 (0.44) | MEN1KMT2ASLC6A4KDM4EMAPT | |
| SCHEMBL3196242 | 0.88 | SLC6A4 (0.46) | MEN1KMT2ASLC6A4KDM4EMAPT | |
| SCHEMBL11761224 | 0.86 | HTR1A (0.51) | MEN1KMT2ASLC6A4KDM4EMAPT | |
| SCHEMBL11705626 | 0.81 | SLC6A4 (0.65) | MEN1KMT2ASLC6A4HPGDCYP1A2 | |
| SCHEMBL11759836 | 0.79 | IDO1 (0.53) | KMT2ASLC6A4PDE7APDE7BRHEB | |
| SCHEMBL11760048 | 0.79 | SLC6A4 (0.43) | SLC6A4KDM4EPDE7APDE7BRHEB | |
| SCHEMBL11576431 | 0.76 | HPGD (0.46) | KMT2ASLC6A4KDM4EMAPTHPGD | |
| SCHEMBL11761184 | 0.75 | ATM (0.46) | MEN1KMT2ASLC6A4KDM4EMAPT | |
| SCHEMBL7318881 | 0.74 | HIF1A (0.41) | MEN1KMT2ASLC6A4KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4044010-A | NEUROLEPTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-3954764-A | NEUROLEPTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1976-05-04 | — | — | US | disclosed |