Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11758917 | 0.88 | MEN1 (0.50) | SLC6A4CYP3A4CYP2C9KMT2AHPGD | |
| SCHEMBL6299244 | 0.83 | SLC6A4 (0.44) | SLC6A4CYP3A4CYP2C9HIF1AKMT2A | |
| SCHEMBL11757703 | 0.82 | SLC6A4 (0.44) | SLC6A4CYP3A4CYP2C9KMT2AHPGD | |
| SCHEMBL11759797 | 0.82 | MEN1 (0.44) | SLC6A4CYP3A4CYP2C9KMT2AHPGD | |
| SCHEMBL7318881 | 0.81 | HIF1A (0.41) | SLC6A4CYP3A4CYP2C9HIF1AKMT2A | |
| SCHEMBL4440726 | 0.80 | SLC6A4 (0.66) | SLC6A4CYP3A4CYP2C9HIF1AKMT2A | |
| SCHEMBL11760048 | 0.78 | SLC6A4 (0.43) | SLC6A4PLA2G1BATG4BSLC6A2SLC6A3 | |
| SCHEMBL11759836 | 0.78 | IDO1 (0.53) | SLC6A4KMT2ASLC6A2SLC6A3IDO1 | |
| SCHEMBL15653298 | 0.77 | IDO1 (0.40) | CYP3A4CYP2C9HIF1AKMT2AHPGD | |
| SCHEMBL15653495 | 0.77 | IDO1 (0.40) | CYP3A4CYP2C9HIF1AKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035951-A1 | 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | NEUROSEARCH A/S (DK) | 2010-02-11 | — | — | US | disclosed |
| EP-2041096-A1 | 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL- CONDUCTANCE CALCIUM-ACTIVATED POTATIUM CHANNELS | NeuroSearch AS (DK) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008003752-A1 | 2 -AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL - CONDUCTANCE CALCIUM -ACT IVATED POTASSIUM CHANNELS | NEUROSEARCH A/S (DK) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035951-A1 | 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | KCNN2, KCNN1, KCNN3 | SLC6A4 1050/4885CYP3A4 1188/4885CYP2C9 1851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.