Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 7/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11325806 | 0.93 | KCNK3 (0.55) | KCNK3KCNK9USP2HSD17B10RAB9A | |
| SCHEMBL11154551 | 0.87 | POLB (0.52) | KCNK3KCNK9USP2HSD17B10RAB9A | |
| SCHEMBL8356134 | 0.86 | KCNK3 (0.63) | KCNK3KCNK9USP2BCHERAB9A | |
| SCHEMBL11403004 | 0.85 | KCNK3 (0.55) | KCNK3KCNK9USP2BCHERAB9A | |
| SCHEMBL11073915 | 0.85 | ALDH1A1 (0.49) | USP2HSD17B10RAB9AGFERALDH1A1 | |
| SCHEMBL11153270 | 0.84 | POLB (0.49) | USP2HSD17B10RAB9AHPGDGFER | |
| SCHEMBL11335964 | 0.82 | SIRT2 (0.49) | KCNK3USP2HSD17B10RAB9ANPC1 | |
| SCHEMBL11401277 | 0.82 | ALDH1A1 (0.47) | USP2HSD17B10RAB9ANPC1HPGD | |
| SCHEMBL11319993 | 0.81 | SMN1; SMN2 (0.58) | HSD17B10RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL10800110 | 0.81 | KCNK3 (0.59) | KCNK3KCNK9RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4006178-A | Process for the manufacture of dicyanovinyl compounds | CIBA-GEIGY CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |