Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 9/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11759949 | 0.93 | KCNK3 (0.50) | KCNK3KCNK9USP2HSD17B10RAB9A | |
| SCHEMBL11154551 | 0.92 | POLB (0.52) | KCNK3KCNK9USP2HSD17B10RAB9A | |
| SCHEMBL11335964 | 0.89 | SIRT2 (0.49) | KCNK3USP2HSD17B10RAB9ANPC1 | |
| SCHEMBL11867225 | 0.84 | KCNK3 (0.61) | KCNK3KCNK9RAB9ANPC1HPGD | |
| SCHEMBL10383523 | 0.83 | HSD17B10 (0.50) | USP2HSD17B10RAB9AHPGDKMT2A | |
| SCHEMBL10800110 | 0.83 | KCNK3 (0.59) | KCNK3KCNK9RAB9ANPC1HPGD | |
| SCHEMBL11795444 | 0.81 | RAB9A (0.58) | KCNK3KCNK9RAB9ANPC1HPGD | |
| SCHEMBL11709369 | 0.80 | KCNK3 (0.64) | KCNK3KCNK9RAB9ANPC1HPGD | |
| SCHEMBL8356134 | 0.80 | KCNK3 (0.63) | KCNK3KCNK9USP2RAB9ANPC1 | |
| SCHEMBL11329299 | 0.79 | LMNA (0.55) | USP2HSD17B10RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243584-A | Monoazo dyestuffs containing diazo component substituted by disulfimide and trifluoromethyl groups | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-06 | — | — | US | disclosed |
| EP-0014031-A1 | Water-soluble monoazo dyes of the azobenzene series, their preparation and process for the colouration of polyamide textile materials | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-08-06 | — | — | EP | disclosed |
| US-4159265-A | Phenylazopyrazolo dyestuffs including disulfimide substituent | BAYER AKTIENGESELLSCHAFT (DE) | 1979-06-26 | — | — | US | disclosed |
| US-4022763-A | Sulfaphenyl-azo-phenyl-azo-aminophenyl dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-10 | — | — | US | disclosed |
| US-3978039-A | POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-24 | — | — | US | disclosed |