Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.68 |
| ▸ | RELA | Q04206 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20691197 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9AHTTGAA | |
| SCHEMBL20284039 | 0.82 | NPC1 (0.70) | SMN1; SMN2NPC1RAB9AHTTGAA | |
| SCHEMBL3713301 | 0.82 | NPC1 (0.70) | SMN1; SMN2NPC1RAB9AHTTGAA | |
| SCHEMBL23336506 | 0.82 | NPC1 (0.60) | SMN1; SMN2NPC1RAB9AHTTGAA | |
| SCHEMBL7470743 | 0.81 | TGM2 (0.67) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL4135335 | 0.81 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9AHTTGAA | |
| SCHEMBL5645657 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9AHTTGAA | |
| SCHEMBL17675351 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9AHTTGAA | |
| SCHEMBL2998577 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9AHTTGAA | |
| SCHEMBL11754128 | 0.80 | KMT2A (1.00) | SMN1; SMN2NPC1RAB9AHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010191-A | Acyl derivatives of substituted bis-arylalkylamino compounds | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-03-01 | — | — | US | disclosed |