Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.68 |
| ▸ | RELA | Q04206 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713301 | 0.82 | NPC1 (0.70) | SMN1; SMN2NPC1RAB9AHTTTSHR | |
| SCHEMBL20284039 | 0.82 | NPC1 (0.70) | SMN1; SMN2NPC1RAB9AHTTTSHR | |
| SCHEMBL5645657 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9AHTTTSHR | |
| SCHEMBL2998577 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9AHTTTSHR | |
| SCHEMBL11759969 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9AHTTTSHR | |
| SCHEMBL4135335 | 0.81 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9AHTTTSHR | |
| SCHEMBL396577 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AHTTTSHR | |
| SCHEMBL7679084 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AHTTTSHR | |
| SCHEMBL7868204 | 0.78 | RAB9A (0.64) | SMN1; SMN2NPC1RAB9AHTTTSHR | |
| SCHEMBL2205368 | 0.78 | TGM2 (0.67) | SMN1; SMN2NPC1RAB9AHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3496711-B1 | SYNTHETIC RETINOIDS (IN CELL MODULATION) | UNIV DURHAM (GB) | 2026-03-18 | — | — | EP | disclosed |
| CN-109843291-B | Synthetic retinoids (cell modulation) | 杜伦大学 | 2024-06-25 | — | — | CN | disclosed |
| US-11833203-B2 | Synthetic retinoids (in cell modulation) | UNIVERSITY OF DURHAM | 2023-12-05 | — | — | US | disclosed |
| US-11833203-B2 | Synthetic retinoids (in cell modulation) | UNIVERSITY OF DURHAM | 2023-12-05 | — | — | US | disclosed |
| US-11833203-B2 | Synthetic retinoids (in cell modulation) | UNIVERSITY OF DURHAM | 2023-12-05 | — | — | US | disclosed |
| US-11324825-B2 | Synthetic retinoids (in cell modulation) | UNIVERSITY OF DURHAM | 2022-05-10 | — | — | US | disclosed |
| US-11324825-B2 | Synthetic retinoids (in cell modulation) | UNIVERSITY OF DURHAM | 2022-05-10 | — | — | US | disclosed |
| EP-3204357-B1 | FLUORESCENT SYNTHETIC RETINOIDS | HIGH FORCE RES LIMITED (GB) | 2022-01-19 | — | — | EP | disclosed |
| EP-3204357-B1 | FLUORESCENT SYNTHETIC RETINOIDS | HIGH FORCE RES LIMITED (GB) | 2022-01-19 | — | — | EP | disclosed |
| CN-107250112-B | Fluorescent synthetic retinoids | 高力研究有限公司 | 2021-04-23 | — | — | CN | disclosed |
| EP-3496711-A1 | SYNTHETIC RETINOIDS (IN CELL MODULATION) | University Of Durham (GB) | 2019-06-19 | — | — | EP | disclosed |
| CN-109843291-A | synthetic retinoids (cell modulation) | 杜伦大学 | 2019-06-04 | — | — | CN | disclosed |
| WO-2018029473-A1 | SYNTHETIC RETINOIDS (IN CELL MODULATION) | UNIVERSITY OF DURHAM (GB) | 2018-02-15 | — | — | WO | disclosed |
| WO-2018029473-A1 | SYNTHETIC RETINOIDS (IN CELL MODULATION) | UNIVERSITY OF DURHAM (GB) | 2018-02-15 | — | — | WO | disclosed |
| CN-107250112-A | Fluorescence synthesizes retinoid | 高力研究有限公司 | 2017-10-13 | — | — | CN | disclosed |
| EP-3204357-A2 | FLUORESCENT SYNTHETIC RETINOIDS | High Force Research Limited (GB) | 2017-08-16 | — | — | EP | disclosed |
| US-20170217893-A1 | Fluorescent Synthetic Retinoids | HIGH FORCE RESEARCH LIMITED (GB) | 2017-08-03 | — | — | US | disclosed |
| US-20170217893-A1 | Fluorescent Synthetic Retinoids | HIGH FORCE RESEARCH LIMITED (GB) | 2017-08-03 | — | — | US | disclosed |
| US-20170217893-A1 | Fluorescent Synthetic Retinoids | HIGH FORCE RESEARCH LIMITED (GB) | 2017-08-03 | — | — | US | disclosed |
| WO-2016055800-A2 | FLUORESCENT SYNTHETIC RETINOIDS | HIGH FORCE RESEARCH LIMITED (GB) | 2016-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11833203-B2 | Synthetic retinoids (in cell modulation) | RARA, RARB, RXRA | SMN1; SMN2 2432/4885NPC1 1449/4885RAB9A 848/4885 |
| US-11324825-B2 | Synthetic retinoids (in cell modulation) | RARA, RARB, RXRA | SMN1; SMN2 2432/4885NPC1 1449/4885RAB9A 848/4885 |
| US-20170217893-A1 | Fluorescent Synthetic Retinoids | RARB, RXRB, RXRA | SMN1; SMN2 2088/4885NPC1 1401/4885RAB9A 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.