Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711618 | 0.84 | KDM4E (0.56) | KDM4ESMN1; SMN2ALDH1A1GAACYP2C19 | |
| SCHEMBL2871452 | 0.74 | KDM4E (0.61) | KDM4ESMN1; SMN2ALDH1A1GAACYP2C19 | |
| SCHEMBL5367724 | 0.72 | KDM4E (0.63) | KDM4ESMN1; SMN2ALDH1A1GAACYP2C19 | |
| SCHEMBL422634 | 0.72 | KDM4E (0.63) | KDM4ESMN1; SMN2ALDH1A1GAACYP2C19 | |
| SCHEMBL19797901 | 0.72 | APOBEC3A (0.41) | KDM4ESMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL2202785 | 0.72 | APOBEC3A (0.41) | ALDH1A1LMNAKMT2A | |
| SCHEMBL13030147 | 0.72 | APOBEC3A (0.49) | KDM4ESMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL13651663 | 0.72 | APOBEC3A (0.41) | SMN1; SMN2ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL27774137 | 0.71 | CYP2C19 (0.39) | KDM4ESMN1; SMN2ALDH1A1GAACYP2C19 | |
| SCHEMBL9453945 | 0.71 | KDM4E (0.61) | KDM4ESMN1; SMN2ALDH1A1GAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042703-A | 4-NITRO-5-CARBAMOYL-IMIDAZOLE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1977-08-16 | — | — | US | claimed |
| US-4042703-A | 4-NITRO-5-CARBAMOYL-IMIDAZOLE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1977-08-16 | — | — | US | disclosed |