Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 4/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375007 | 0.82 | APOBEC3A (0.38) | APOBEC3AAPOBEC3GMEN1PABPC1KMT2A | |
| SCHEMBL3054669 | 0.81 | APOBEC3A (0.42) | APOBEC3AAPOBEC3GKMT2ALMNAALDH1A1 | |
| SCHEMBL23716719 | 0.79 | APOBEC3A (0.41) | APOBEC3AAPOBEC3GKMT2ALMNAALDH1A1 | |
| SCHEMBL13651663 | 0.79 | APOBEC3A (0.41) | APOBEC3AAPOBEC3GMEN1PABPC1KMT2A | |
| SCHEMBL13030147 | 0.79 | APOBEC3A (0.49) | APOBEC3AAPOBEC3GMEN1PABPC1KMT2A | |
| SCHEMBL2202785 | 0.79 | APOBEC3A (0.41) | APOBEC3AAPOBEC3GMEN1PABPC1KMT2A | |
| SCHEMBL23367000 | 0.79 | APOBEC3A (0.41) | APOBEC3AAPOBEC3GLMNAALDH1A1DPP4 | |
| SCHEMBL20360594 | 0.79 | KDM4E (0.49) | APOBEC3AAPOBEC3GKMT2AALDH1A1KDM4E | |
| SCHEMBL23716720 | 0.78 | APOBEC3A (0.40) | APOBEC3AAPOBEC3GLMNAALDH1A1CTDSP1 | |
| SCHEMBL28415122 | 0.78 | APOBEC3A (0.40) | APOBEC3AAPOBEC3GMEN1PABPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024261328-A1 | AMIDE-AMINE COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2024-12-26 | — | — | WO | disclosed |
| EP-3487840-B1 | CYCLOHEXYL BENZAMIDE COMPOUNDS | LILLY CO ELI (US) | 2021-08-11 | — | — | EP | disclosed |
| WO-2018014800-A1 | CYCLOHEXYL BENZAMIDE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2018-01-25 | — | — | WO | disclosed |