Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11759370 | 0.92 | RORC (0.56) | RORCALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL11757920 | 0.87 | RORC (0.45) | RORCALDH1A1LMNAHTTKMT2A | |
| SCHEMBL11758621 | 0.87 | RORC (0.45) | RORCALDH1A1LMNAHTTKMT2A | |
| SCHEMBL30601164 | 0.87 | KMT2A (0.58) | RORCALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL395886 | 0.87 | KMT2A (0.58) | RORCALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL395887 | 0.87 | KMT2A (0.58) | RORCALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL11764096 | 0.84 | MEN1 (0.41) | RORCALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL11758050 | 0.84 | LMNA (0.42) | RORCALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL11758286 | 0.81 | MEN1 (0.45) | RORCALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL11258075 | 0.80 | TP53 (0.55) | RORCALDH1A1TP53LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032657-A | FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1977-06-28 | — | — | US | claimed |
| US-4032657-A | FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |