Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2197988 | 0.86 | MAPK14 (0.58) | MAOBMAPTATMSMN1; SMN2MAPK14 | |
| SCHEMBL1917308 | 0.77 | MAOB (0.48) | MAOBMAPTATMSMN1; SMN2MAPK14 | |
| SCHEMBL995811 | 0.76 | HTR2B (0.46) | MAOBMAPTATMSMN1; SMN2MAPK14 | |
| SCHEMBL14313466 | 0.76 | GAA (0.39) | MAOBMAPTATMSMN1; SMN2MAPK14 | |
| SCHEMBL7206976 | 0.76 | HTR2B (0.46) | MAOBMAPTATMSMN1; SMN2MAPK14 | |
| SCHEMBL995810 | 0.76 | HTR2B (0.46) | MAOBMAPTATMSMN1; SMN2MAPK14 | |
| SCHEMBL29361803 | 0.76 | MAOB (0.47) | MAOBMAPTATMSMN1; SMN2MAPK14 | |
| SCHEMBL905642 | 0.76 | MAOB (0.47) | MAOBMAPTATMSMN1; SMN2MAPK14 | |
| SCHEMBL14288484 | 0.74 | HTR2B (0.47) | MAOBMAPTATMSMN1; SMN2KMT2A | |
| SCHEMBL10702618 | 0.72 | MAPK14 (0.55) | MAOBMAPTATMSMN1; SMN2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4020163-A | Use of heterocyclic esters of 5H-[1]benzopyrano [3,4-b]pyridines as analgesics | SHARPS ASSOCIATES (US) | 1977-04-26 | — | — | US | disclosed |