SCHEMBL905642

SCHEMBL905642

O=C1OCc2ncccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.47
MAOA P21397 1/20 0.47
GAA P10253 2/20 0.43
TDP2 O95551 1/20 0.43
NSD2 O96028 1/20 0.43
ABL1 P00519 1/20 0.43
PLCG1 P19174 1/20 0.43
CES1 P23141 1/20 0.43
PAX8 Q06710 1/20 0.43
RIN1 Q13671 1/20 0.43
MEN1 O00255 1/20 0.43
THRB P10828 1/20 0.43
BLM P54132 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPK14 Q16539 3/20 0.43
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
KDM4E B2RXH2 1/20 0.40
TYMS P04818 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29361803 1.00 MAOB (0.47) MAOBMAOAGAATDP2NSD2
SCHEMBL29448312 0.80 TDP2 (0.45) MAOBMAOAGAATDP2NSD2
SCHEMBL15509407 0.80 TDP2 (0.45) MAOBMAOAGAATDP2NSD2
SCHEMBL2197988 0.78 MAPK14 (0.58) MAOBGAAMEN1KMT2ATDP1
SCHEMBL22990892 0.76 TDP2 (0.50) MAOBMAOAGAATDP2NSD2
SCHEMBL11760554 0.76 MAOB (0.45) MAOBMAOAGAAMEN1THRB
SCHEMBL7413469 0.76 TDP2 (0.41) MAOBGAATDP2NSD2ABL1
SCHEMBL31064536 0.76 TDP2 (0.41) MAOBGAATDP2NSD2ABL1
SCHEMBL19140159 0.73 MAOB (0.41) MAOBMAOAGAAKMT2AALDH1A1
SCHEMBL14062663 0.72 MAPK14 (0.36) MAOBMAOAGAATDP2NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3859211-B1 HANDHELD LIGHTER WITH HIGH TEMPERATURE WARNING INDICATOR SOCIéTé BIC (FR) 2024-01-24 EP claimed
EP-3858925-B1 IRREVERSIBLY ERASABLE INK COMPOSITION COMPRISING A DISCOLORATION AGENT SOCIéTé BIC (FR) 2023-01-11 EP claimed
EP-3904468-B1 METHOD FOR PREPARING THERMOCHROMIC WATER-BASED GEL INK COMPOSITIONS, AND THERMOCHROMIC WATER-BASED GEL INK COMPOSITIONS THEREOF SOCIéTé BIC (FR) 2022-10-19 EP claimed
EP-3856855-B1 DIESTER OF BISPHENOL FLUORENE COMPOUNDS AND THERMOCHROMIC PIGMENT COMPOSITIONS COMPRISING THE SAME SOCIéTé BIC (FR) 2022-07-20 EP claimed
EP-3829893-B1 ERASING TOOL CONTAINING POLYETHERAMINE FOR THERMOCHROMIC INK COMPOSITIONS SOCIéTé BIC (FR) 2022-04-27 EP claimed
CN-111527084-A Isofuranone compounds useful as HPK1 inhibitors 百时美施贵宝公司 2020-08-11 CN claimed
EP-0319283-B1 THERMALLY RESPONSIVE RECORD MATERIAL APPLETON PAPERS INC. (US) 1993-06-09 EP claimed
US-4675407-A COLOR FORMERS IN PRESSURE SENSITIVE AND HEAT SENSITIVE RECORD ING MATERIALS CIBA-GEIGY CORPORATION (US) 1987-06-23 US claimed
US-4508897-A CONDENSATION OF AN ANILINE AND THE PRODUCT OF A QUINOLINIC ANHYDRI CIBA GEIGY CORPORATION (US) 1985-04-02 US claimed
US-4243250-A FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS STERLING DRUG INC. (US) 1981-01-06 US claimed
JP-5139026-A None JP disclosed
JP-56151597-A None JP disclosed
JP-6199799-A None JP disclosed
US-12575977-B2 Composition for wet indicator HENKEL AG & CO. KGAA (DE) 2026-03-17 US disclosed
US-12552790-B2 Positive modulators of the muscarinic acetylcholine receptor M4 VANDERBILT UNIVERSITY (US) 2026-02-17 US disclosed
US-4508897-A CONDENSATION OF AN ANILINE AND THE PRODUCT OF A QUINOLINIC ANHYDRI CIBA GEIGY CORPORATION (US) 1985-04-02 US disclosed
US-4337340-A FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS STERLING DRUG INC. (US) 1982-06-29 US disclosed
JP-S56151597-A RECORDING MATERIAL YAMAMOTO KAGAKU GOSEI KK 1981-11-24 JP disclosed
US-4243250-A FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS STERLING DRUG INC. (US) 1981-01-06 US disclosed
US-4211872-A COLOR FORMERS FREEDOM CHEMICAL COMPANY 1980-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552790-B2 Positive modulators of the muscarinic acetylcholine receptor M4 CHRM4, CHRM1, CHRM5 MAOB 450/4885MAOA 580/4885GAA 4038/4885
US-12575977-B2 Composition for wet indicator HAO2, ALOX12, CD44 MAOB 4280/4885MAOA 3315/4885GAA 3653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.