Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.79 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14628590 | 0.85 | LMNA (0.76) | LMNASMN1; SMN2MAPK1HTTGAA | |
| SCHEMBL30511126 | 0.81 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2MAPK1HTTGAA | |
| SCHEMBL12233251 | 0.81 | LMNA (0.74) | LMNASMN1; SMN2MAPK1HTTGAA | |
| SCHEMBL2538729 | 0.81 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2MAPK1HTTGAA | |
| SCHEMBL29236768 | 0.80 | LMNA (0.68) | LMNASMN1; SMN2MAPK1HTTGAA | |
| SCHEMBL29689390 | 0.80 | LMNA (0.68) | LMNASMN1; SMN2MAPK1HTTGAA | |
| SCHEMBL11812190 | 0.80 | LMNA (0.68) | LMNASMN1; SMN2MAPK1HTTGAA | |
| SCHEMBL1039742 | 0.79 | SMN1; SMN2 (0.70) | LMNASMN1; SMN2MAPK1HTTGAA | |
| SCHEMBL7821807 | 0.78 | LMNA (0.79) | LMNASMN1; SMN2MAPK1HTTGAA | |
| SCHEMBL30040198 | 0.78 | LMNA (0.79) | LMNASMN1; SMN2MAPK1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4015017-A | Certain biphenyl derivatives used to treat disorders caused by increased capillary permeability | LABORATOIRES PHARMASCIENCE (FR) | 1977-03-29 | — | — | US | disclosed |