Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | HTT | P42858 | 3/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2538729 | 0.87 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2HTTMAPK1GAA | |
| SCHEMBL30511126 | 0.87 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2HTTMAPK1GAA | |
| SCHEMBL12233251 | 0.87 | LMNA (0.74) | LMNASMN1; SMN2HTTMAPK1GAA | |
| SCHEMBL11761322 | 0.85 | LMNA (0.79) | LMNASMN1; SMN2HTTMAPK1GAA | |
| SCHEMBL119395 | 0.82 | CA2 (0.68) | NPC1MAPTRAB9AALDH1A1LDHA | |
| SCHEMBL28170408 | 0.82 | CA2 (0.68) | NPC1MAPTRAB9AALDH1A1LDHA | |
| SCHEMBL29997296 | 0.82 | CA2 (0.68) | NPC1MAPTRAB9AALDH1A1LDHA | |
| SCHEMBL19104759 | 0.81 | HPGDS (0.53) | LMNASMN1; SMN2HTTMAPK1GAA | |
| SCHEMBL19104748 | 0.81 | SMN1; SMN2 (0.51) | LMNASMN1; SMN2HTTMAPK1GAA | |
| SCHEMBL30511135 | 0.81 | SMN1; SMN2 (0.78) | LMNASMN1; SMN2HTTMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1743881-A1 | Phenyl-benzyl-ketones | G.J. Consultants Pty Ltd (AU) | 2007-01-17 | — | — | EP | disclosed |