Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 13/20 | 0.39 |
| ▸ | PGK1 | P00558 | 3/20 | 0.39 |
| ▸ | PGK2 | P07205 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11765728 | 0.90 | FDPS (0.42) | FDPSPGK1PGK2ESR1ESR2 | |
| SCHEMBL11762352 | 0.87 | GGPS1 (0.47) | FDPSGGPS1 | |
| SCHEMBL11758058 | 0.87 | FDPS (0.46) | FDPSGGPS1 | |
| SCHEMBL11759309 | 0.85 | PGK1 (0.41) | PGK1PGK2ESR1ESR2 | |
| SCHEMBL11759455 | 0.83 | FDPS (0.46) | FDPSGGPS1 | |
| SCHEMBL11724415 | 0.81 | NPSR1 (0.37) | PGK1PGK2ESR1ESR2 | |
| SCHEMBL11727825 | 0.81 | PGK1 (0.36) | PGK1PGK2 | |
| SCHEMBL11761399 | 0.80 | FDPS (0.52) | FDPSGGPS1 | |
| SCHEMBL11728190 | 0.80 | PGK1 (0.35) | PGK1PGK2 | |
| SCHEMBL11763080 | 0.76 | FDPS (0.42) | FDPSPGK1PGK2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061681-A | Method for the preparation of mono- or poly [dialkyl or dicycloalkylphosphonylmethyl] aromatic carbocyclic compounds | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |