Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11761936 | 1.00 | LMNA (0.38) | LMNABLMKDM1APTPN1CYP3A4 | |
| SCHEMBL11765214 | 0.97 | BLM (0.41) | LMNABLMKDM1APTPN1CYP3A4 | |
| SCHEMBL11765208 | 0.97 | BLM (0.41) | LMNABLMKDM1APTPN1CYP3A4 | |
| SCHEMBL11768073 | 0.86 | LMNA (0.47) | LMNABLMKDM1APTPN1CYP3A4 | |
| SCHEMBL11768079 | 0.86 | LMNA (0.47) | LMNABLMKDM1APTPN1CYP3A4 | |
| SCHEMBL11764072 | 0.86 | KDM1A (0.48) | LMNABLMKDM1APTPN1CYP3A4 | |
| SCHEMBL11764066 | 0.86 | KDM1A (0.48) | LMNABLMKDM1APTPN1CYP3A4 | |
| SCHEMBL11746947 | 0.83 | LMNA (0.47) | LMNABLMKDM1APTPN1CYP3A4 | |
| SCHEMBL11767144 | 0.83 | ALOX15 (0.31) | LMNACYP3A4ALDH1A1TDP1ALOX15 | |
| SCHEMBL11746945 | 0.83 | LMNA (0.47) | LMNABLMKDM1APTPN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021461-A | INSECTICIDES | ZOECON CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |