Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11764467 | 0.90 | ALDH1A1 (0.42) | LMNAALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL11762762 | 0.83 | TSHR (0.38) | LMNAALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL11195466 | 0.76 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL6232304 | 0.76 | LMNA (0.49) | LMNAALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL11182267 | 0.75 | — | — | |
| SCHEMBL11182270 | 0.75 | — | — | |
| SCHEMBL11384893 | 0.73 | TSHR (0.31) | TSHR | |
| SCHEMBL11771126 | 0.73 | TSHR (0.41) | ALDH1A1MAPTTSHR | |
| SCHEMBL11178748 | 0.72 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL8393327 | 0.72 | GBA1 (0.42) | LMNAALDH1A1HPGDTSHRMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024143-A | Silylation of 5-fluoro-6-hydroxy or alkoxy pyrimidine | PCR, INC. (US) | 1977-05-17 | — | — | US | disclosed |