Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.70 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylamine SCHEMBL28471738 | 0.90 | LOXL2 (0.78) | LOXL2TAAR1TSHRHTR2ACYP2A6 | |
| Benzylamine SCHEMBL28619106 | 0.87 | LOXL2 (0.93) | LOXL2TAAR1TSHRHTR2ACYP2A6 | |
| Benzylamine SCHEMBL30045627 | 0.87 | LOXL2 (0.93) | LOXL2TAAR1TSHRHTR2ACYP2A6 | |
| Benzylamine SCHEMBL27781209 | 0.87 | LOXL2 (0.93) | LOXL2TAAR1TSHRHTR2ACYP2A6 | |
| Benzylamine SCHEMBL9483 | 0.87 | — | — | |
| Benzylamine SCHEMBL30098454 | 0.87 | LOXL2 (0.93) | LOXL2TAAR1TSHRHTR2ACYP2A6 | |
| Benzylamine SCHEMBL10942012 | 0.87 | LOXL2 (0.93) | LOXL2TAAR1TSHRHTR2ACYP2A6 | |
| Benzylamine SCHEMBL465924 | 0.87 | LOXL2 (0.93) | LOXL2TAAR1TSHRHTR2ACYP2A6 | |
| Benzylamine SCHEMBL27739746 | 0.87 | LOXL2 (0.93) | LOXL2TAAR1TSHRHTR2ACYP2A6 | |
| Benzylamine SCHEMBL15654117 | 0.87 | LOXL2 (0.93) | LOXL2TAAR1TSHRHTR2ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150216985-A1 | ENDOSPORE COMPOSITIONS AND USES THEREOF | Annuary Healthcare Inc. | 2015-08-06 | — | — | US | disclosed |
| US-20140205546-A1 | NANOSCALE PARTICLE FORMULATIONS AND METHODS | Annuary Healthcare, Inc. | 2014-07-24 | — | — | US | disclosed |
| US-20140178496-A1 | ENDOSPORE COMPOSITIONS AND USES THEREOF | Annuary Healthcare Inc. | 2014-06-26 | — | — | US | disclosed |
| US-20130177504-A1 | Nanoscale Particle Formulations and Methods | Annuary Healthcare, Inc. (US) | 2013-07-11 | — | — | US | disclosed |
| WO-2012174466-A2 | NANOSCALE PARTICLE FORMULATIONS AND METHODS | Annuary Healthcare, Inc. (US) | 2012-12-20 | — | — | WO | disclosed |
| US-4042368-A | Additive for quaternary amine bactericides and algicides, compositions containing same and method of manufacture | EPIC CHEMICAL INC. (US) | 1977-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150216985-A1 | ENDOSPORE COMPOSITIONS AND USES THEREOF | CUTA, SUCLG1, CD47 | LOXL2 2631/4885TAAR1 2745/4885TSHR 4575/4885 |
| US-20140178496-A1 | ENDOSPORE COMPOSITIONS AND USES THEREOF | CUTA, SUCLG1, CD47 | LOXL2 2631/4885TAAR1 2745/4885TSHR 4575/4885 |
| US-20140205546-A1 | NANOSCALE PARTICLE FORMULATIONS AND METHODS | CUTA, S100P, KRT18 | LOXL2 1599/4885TAAR1 2200/4885TSHR 4498/4885 |
| US-20130177504-A1 | Nanoscale Particle Formulations and Methods | CUTA, S100P, KRT18 | LOXL2 1599/4885TAAR1 2200/4885TSHR 4498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.