Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778893 | 0.95 | NLRP3 (0.48) | NLRP3NFKB1NFKB2RELAPPARG | |
| SCHEMBL14635160 | 0.95 | NLRP3 (0.48) | NLRP3NFKB1NFKB2RELAPPARG | |
| SCHEMBL10563923 | 0.94 | NLRP3 (0.50) | NLRP3PPARGPPARDPPARATSHR | |
| SCHEMBL11757215 | 0.83 | NLRP3 (0.46) | NLRP3NFKB1NFKB2RELA | |
| SCHEMBL31592750 | 0.75 | PDCD4 (0.36) | CA1CA2CA9CA12CA3 | |
| SCHEMBL28135018 | 0.74 | SMN1; SMN2 (0.37) | SMN1; SMN2TDP1PPP5C | |
| SCHEMBL10570352 | 0.74 | NLRP3 (0.65) | NLRP3 | |
| SCHEMBL6993914 | 0.73 | — | — | |
| SCHEMBL11765197 | 0.71 | PPARG (0.36) | NFKB1NFKB2RELAPPARGPPARD | |
| SCHEMBL9349887 | 0.70 | GBA1 (0.39) | SMN1; SMN2TSHRTDP1L3MBTL1PPP5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059595-A | Process for preparing 3-oxy-4H-pyran-4-one derivatives | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHI (JA) | 1977-11-22 | — | — | US | disclosed |