SCHEMBL6993914

SCHEMBL6993914

COC1C=CC(=O)CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11757215 0.79 NLRP3 (0.46)
SCHEMBL32679474 0.79 NLRP3 (0.42)
SCHEMBL11759764 0.79 NLRP3 (0.42)
SCHEMBL10571332 0.78 NLRP3 (0.45)
SCHEMBL2951827 0.77 NLRP3 (0.55)
SCHEMBL2951820 0.77 NLRP3 (0.55)
SCHEMBL13734264 0.74 NLRP3 (0.39)
SCHEMBL10573770 0.73 NLRP3 (0.44)
SCHEMBL11763545 0.73 NLRP3 (0.46)
SCHEMBL14634399 0.73 NLRP3 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-54044675-A None JP disclosed
CN-121574135-A Method for synthesizing 7-oxa-2-azabicyclo [3.3.1] non-3-alkene-1-alcohol by rare earth catalysis 北京化工大学 2026-02-27 CN disclosed
US-6506911-B2 Reacting a 2-(1-hydroxyalkyl)-3-hydroxypyran-4(1H)one compound with benzaldehyde dimethyl acetal to form 8-oxo-4,8-dihydro-2-phenyl-4h(3,2-d)-m-dioxin, reacting it with an amine compound to form an intermediate, then reducing BTG INTERNATIONAL LIMITED (GB) 2003-01-14 US disclosed
EP-0984934-B1 NOVEL ORALLY ACTIVE IRON (III) CHELATORS BTG INTERNAT LTD COMPANY NO 26 (GB) 2003-01-08 EP disclosed
US-6448273-B1 SUCH AS 2,6-DIMETHOXYMETHYL-1-METHYL-3-BENZYLOXPYRIDIN-4(1H)-ONE; TREATING DISORDERS ASSOCIATED WITH IRON DISTRIBUTION AND IRON DEPENDANT PARASITES; REDUCED LEVELS OF ACTIVE AGENT; SELECTIVE TARGETING TO TISSUES AND LIVER; METABOLIC STABILITY BTG INTERNATIONAL LIMITED (GB) 2002-09-10 US disclosed
US-20020068758-A1 Novel orally active iron (III) chelators BTG INTERNATIONAL LIMITED. 2002-06-06 US disclosed
US-6335353-B1 3-HYDROXYPYRIDIN-4-ONE DERIVATIVE; IRON DEFICIENCY ANEMIA AND THALASSEMIA TREATMENT BTG INTERNATIONAL LIMITED (GB) 2002-01-01 US disclosed
EP-0984934-A1 NOVEL ORALLY ACTIVE IRON (III) CHELATORS BTG INTERNATIONAL LIMITED (Company No. 2664412) (GB) 2000-03-15 EP disclosed
WO-1998054138-A1 NOVEL ORALLY ACTIVE IRON (III) CHELATORS BTG INTERNATIONAL LIMITED (GB) 1998-12-03 WO disclosed
JP-S5444675-A PRODUCTION OF 3-HYDROXY-4-PYRONE ANALOG SHIN ETSU CHEM CO LTD 1979-04-09 JP disclosed
US-4059595-A Process for preparing 3-oxy-4H-pyran-4-one derivatives OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHI (JA) 1977-11-22 US disclosed