Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | HTR1B | P28222 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6649844 | 0.89 | L3MBTL1 (0.67) | KDM4EHTR1BL3MBTL1MAPTMAPK1 | |
| SCHEMBL17334590 | 0.89 | L3MBTL1 (0.67) | KDM4EHTR1BL3MBTL1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL4383401 | 0.87 | L3MBTL1 (0.65) | KDM4EHTR1BL3MBTL1MAPTMAPK1 | |
| SCHEMBL8834938 | 0.86 | KDM4E (0.95) | KDM4EHTR1BL3MBTL1MAPTTP53 | |
| SCHEMBL31050988 | 0.86 | KDM4E (0.95) | KDM4EHTR1BL3MBTL1MAPTTP53 | |
| SCHEMBL17334594 | 0.85 | HTR1A (0.56) | KDM4EHTR1BL3MBTL1MAPTMAPK1 | |
| SCHEMBL15923299 | 0.85 | MEN1 (0.58) | KDM4EHTR1BL3MBTL1MAPTLMNA | |
| SCHEMBL11522977 | 0.85 | KDM4E (0.55) | KDM4EHTR1BTP53MAPK1RAB9A | |
| Hydrochloric Acid SCHEMBL4372684 | 0.84 | L3MBTL1 (0.61) | KDM4EHTR1BL3MBTL1TP53MAPK1 | |
| SCHEMBL1249120 | 0.84 | HTR1B (0.56) | KDM4EHTR1BL3MBTL1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051166-A | Araliphatic diisocyanates | THE UPJOHN COMPANY (US) | 1977-09-27 | — | — | US | disclosed |