Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11763596 | 1.00 | MAPT (0.46) | MAPTSMN1; SMN2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL11765202 | 0.90 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL28548771 | 0.82 | TSHR (0.61) | MAPTSMN1; SMN2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL28796689 | 0.78 | F2R (0.46) | ALDH1A1L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL32688037 | 0.77 | TSHR (0.52) | MAPTALDH1A1TP53MEN1KMT2A | |
| SCHEMBL406193 | 0.76 | ERCC5 (0.59) | SMN1; SMN2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL31388602 | 0.74 | TSHR (0.72) | ALDH1A1L3MBTL1LMNAMAPK1TP53 | |
| SCHEMBL29363601 | 0.74 | IDE (0.54) | MAPTSMN1; SMN2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL17861210 | 0.74 | TSHR (0.52) | SMN1; SMN2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL11772453 | 0.74 | NPC1 (0.53) | MAPTSMN1; SMN2ALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032503-A | TRIAZOLE RING | CIBA-GEIGY CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |