Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11759399 | 0.87 | ENPP2 (0.68) | ENPP2PRMT1APEX1 | |
| SCHEMBL11759424 | 0.87 | ENPP2 (0.68) | ENPP2PRMT1APEX1 | |
| SCHEMBL11764265 | 0.86 | ENPP2 (0.72) | ENPP2PRMT1APEX1 | |
| SCHEMBL11764643 | 0.81 | APEX1 (0.56) | ENPP2APEX1KMT2AMEN1POLB | |
| SCHEMBL11764638 | 0.81 | APEX1 (0.56) | ENPP2APEX1KMT2AMEN1POLB | |
| SCHEMBL11759303 | 0.79 | ENPP2 (0.65) | ENPP2PRMT1APEX1 | |
| SCHEMBL11759329 | 0.79 | ENPP2 (0.65) | ENPP2PRMT1APEX1 | |
| SCHEMBL11761477 | 0.79 | HSD17B10 (0.41) | ENPP2PRMT1APEX1KMT2AMEN1 | |
| SCHEMBL10891071 | 0.74 | ENPP2 (0.85) | ENPP2PRMT1APEX1MAPK1 | |
| SCHEMBL11594349 | 0.74 | ENPP2 (0.85) | ENPP2PRMT1APEX1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4049640-A | Substituted bisnaphthylazo diphenyl ureido complement inhibitors | AMERICAN CYANAMID COMPANY (US) | 1977-09-20 | — | — | US | disclosed |