Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11764643 | 1.00 | APEX1 (0.56) | APEX1ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL11765774 | 0.87 | APEX1 (0.65) | APEX1ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL11765761 | 0.87 | APEX1 (0.65) | APEX1ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL11761475 | 0.81 | ENPP2 (0.52) | APEX1MEN1KMT2APOLBENPP2 | |
| SCHEMBL11764842 | 0.79 | APEX1 (0.62) | APEX1ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL11764830 | 0.79 | APEX1 (0.62) | APEX1ALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL11760573 | 0.73 | APEX1 (0.61) | APEX1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11760582 | 0.73 | APEX1 (0.61) | APEX1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11758267 | 0.73 | APEX1 (0.77) | APEX1ALDH1A1CYP3A4ALOX15MEN1 | |
| SCHEMBL3410648 | 0.73 | APEX1 (0.77) | APEX1ALDH1A1CYP3A4ALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4049640-A | Substituted bisnaphthylazo diphenyl ureido complement inhibitors | AMERICAN CYANAMID COMPANY (US) | 1977-09-20 | — | — | US | disclosed |